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Codeine - Purchase Online
Brand and Generic names: Codeine
Systematic (IUPAC) name:
(5α,6α)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
Chemical Formula: C18H21NO3
Codeine is an opiate used to treat mild to moderate pain. It may be used for irritable bowel syndrome treatment. Approved indications for Codeine include cough, though its efficacy in low dose over the counter formulations has been disputed. It is also used for its antidiarrheal properties.
Codeine is marketed as the salts Codeine sulphate and Codeine phosphate in the United States and Canada. Codeine hydrochloride is more commonly marketed in continental Europe and other regions, and Codeine hydroiodide and Codeine bitartrate round out the top five most-used codeine salts worldwide.
Codeine is from 8 to 12 percent of the strength of morphine in most people. It is the starting material and prototype of a large class of mainly mild to moderately strong opioids such as Hydrocodone, Dihydrocodeine and its derivatives such as Nicocodeine, Oxycodone, etc.
Codeine is sometimes marketed in combination preparations with the analgesic, acetaminophen (paracetamol), as co-codamol, paracod, panadeine, or Tylenol 3, with the analgesic, acetylsalicylic acid (aspirin), as co-codaprin or with the NSAID (non-steroidal anti-inflammatory drug), ibuprofen, as Herron Blue or Nurofen Plus. These combinations provide greater pain relief than either agent alone (drug synergy). Codeine is also commonly compounded with other pain killers or muscle relaxers such as Fioricet with Codeine, Soma Compound/Codeine, etc.
In some countries Codeine is easily available over the counter or on prescription in combination products like cough syrups, etc. However, in Australia, New Zealand, The United Kingdom, Romania, Canada and many other countries, Codeine is regulated.
In the United States, Codeine is regulated by the Controlled Substances Act.It is a controlled substance for pain-relief products. In some states may be dispensed in amounts up to 4 fl. oz. per 48 hours without a prescription.
In Germany, Switzerland and Austria, Codeine and the similarly-named narcotics are controlled substances.
Therapeutic use of Codeine falls in the category of 10-60 mg at once for the starting dose. Tolerance can build with time. The ceiling for Codeine use in the clinical setting is often set at 120 mg per dose and 640-1000 mg per 24 hours and/or the 1000 mg/dose and 4000 mg per day limit for paracetamol as histamine-related side effects may become difficult to manage and are not as likely to decrease with time as much as the direct narcotic effects.
The recreational dose of Codeine is between 60 mg and 400 mg; the liver cannot metabolize any more than that amount at once. This is also the reason for which the entire dose should be taken at one time and at least two hours allowed between doses.
Codeine may be habit-forming and should be used only by the person it was prescribed for. Codeine should never be given to another person, especially someone who has a history of drug abuse or addiction.
Codeine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Do not use Codeine if you have ever had an allergic reaction to a narcotic medicine (including codeine, methadone, morphine, Oxycontin, Darvocet, Percocet, Vicodin, Lortab, and many others). You should also not take Codeine if you are having an asthma attack or if you have a bowel obstruction called paralytic ileus.
Before using codeine, tell your doctor if you are allergic to any drugs, or if you have:
Codeine may be harmful to an unborn baby, and could cause breathing problems or addiction/withdrawal symptoms in a newborn. Tell your doctor if you are pregnant or plan to become pregnant or breast-feed your baby during treatment.
Overdose symptoms may include extreme drowsiness, pinpoint pupils, confusion, cold and clammy skin, weak pulse, shallow breathing, fainting, or breathing that stops.
Do not drink alcohol while you are taking this medication. Dangerous side effects or death can occur when alcohol is combined with codeine.
This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
Less serious side effects include:
Do not take Codeine with other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.
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